Gallager R L, Helwig E B
Am J Clin Pathol. 1980 Dec;74(6):759-64. doi: 10.1093/ajcp/74.6.759.
Fifty-three examples of a benign tumor of nerve sheath origin occurring in the dermis are described. Tumors were usually initially noticed by patients in the first or second decade of life. The tumors tended to occur in the central area of the face, arms, and shoulders. There was a 4.3/1 female to male predominance among affected patients. Histologically, these lesions contained nests and cords of large cells in a variably mucinous matrix. In a number of instances, a close histologic relationship existed between tumor cells and small nerves. Despite nuclear atypia and a variable number of mitotic figures, the tumors have behaved in a benign fashion. To our knowledge only two recurred, and inadequate excision was the apparent cause. We propose the name "neurothekeoma" for these tumors (Gr. Oeke, "sheath").
本文描述了53例起源于神经鞘的良性肿瘤，这些肿瘤发生于真皮层。患者通常在生命的第一个或第二个十年首次发现这些肿瘤。肿瘤倾向于发生在面部、手臂和肩部的中央区域。在受影响的患者中，女性与男性的比例为4.3/1。组织学上，这些病变在不同程度的黏液基质中含有大细胞巢和索条。在许多情况下，肿瘤细胞与小神经之间存在密切的组织学关系。尽管存在核异型性和数量不等的有丝分裂象，但这些肿瘤表现为良性。据我们所知，只有两例复发，明显原因是切除不彻底。我们建议将这些肿瘤命名为“神经鞘瘤”（希腊语：Oeke，“鞘”）。
