Giorno R, Clifford J H, Beverly S, Rossing R G
Am J Clin Pathol. 1980 Dec;74(6):765-70. doi: 10.1093/ajcp/74.6.765.
The following hematologic parameters in 1,744 healthy men and women aged 16 to 89 years were studied: leukocyte count, erythrocyte count, hemoglobin, hematocrit, mean cell volume (MCV), mean cell hemoglobin (MCH), and mean cell hemoglobin concentration. The frequency distributions of all parameters were statistically significantly deviated from Gaussian distributions. Standard Gaussian statistical methods as well as nonparametric methods were used to establish 95% reference intervals for each parameter. The effects of sex and age upon these parameters were also studied. Significant age differences, which were most striking for leukocyte count, erythrocyte count, MCV, and MCH, were detected.
对1744名年龄在16至89岁的健康男性和女性的以下血液学参数进行了研究：白细胞计数、红细胞计数、血红蛋白、血细胞比容、平均细胞体积（MCV）、平均细胞血红蛋白（MCH）和平均细胞血红蛋白浓度。所有参数的频率分布均在统计学上显著偏离高斯分布。使用标准高斯统计方法以及非参数方法为每个参数建立95%参考区间。还研究了性别和年龄对这些参数的影响。检测到显著的年龄差异，其中白细胞计数、红细胞计数、MCV和MCH的差异最为明显。
