Berger H, Tsambaos D, Mahrle G
Arch Dermatol Res. 1980;269(1):39-49. doi: 10.1007/BF00404456.
The effect of long-term ultraviolet irradiation on the connective tissue of the skin was investigated in 25 naked (Ng/-) mice which received a total daily radiant dose of 40 +/- 2 J/cm2 for a period of 8.5 months. The produced alterations were very similar to those found in actinic elastosis of humans, as assessed by histologic and electron-microscopic criteria.
在25只裸鼠(Ng/-)中研究了长期紫外线照射对皮肤结缔组织的影响,这些裸鼠每天接受的总辐射剂量为40±2 J/cm²,持续8.5个月。根据组织学和电子显微镜标准评估,所产生的变化与人类光化性弹性组织变性中发现的变化非常相似。