Marcus J C, Pettifor J M
Arch Neurol. 1980 Dec;37(12):772-4. doi: 10.1001/archneur.1980.00500610052008.
Ninety poorly nourished, ambulant, epileptic children, who had been receiving anticonvulsant medications for at least one year, were studied in respect to their folic acid and vitamin D metabolism. Only 11 (12.2%) had borderline or low folate levels. Serum vitamin D levels were low in five (8.9%); serum calcium levels were low in nine (10%); and serum phosphorus levels were low in three (3.3%). Alkaline phosphatase levels were elevated in 19 (21.1%), but whether these arose from bone or liver was ot determined. Height retardation did not correlate with abnormal mineral metabolism.
对90名营养不良、能行走、患有癫痫且已接受抗惊厥药物治疗至少一年的儿童进行了叶酸和维生素D代谢方面的研究。只有11名(12.2%)儿童的叶酸水平处于临界值或偏低。5名(8.9%)儿童的血清维生素D水平较低;9名(10%)儿童的血清钙水平较低;3名(3.3%)儿童的血清磷水平较低。19名(21.1%)儿童的碱性磷酸酶水平升高,但这些升高是源于骨骼还是肝脏尚未确定。身高发育迟缓与矿物质代谢异常无关。