Ciraolo O, Carrozza G, Petrelli L, Scuderi C, Giarrizzo S, Nicita Mauro V, Ceruso D
Boll Soc Ital Biol Sper. 1980 Jun 15;56(11):1157-63.
By hystological and electronmicroscopical study liver of rats treated with tiadenol at a daily dose of 100 and 200 mg for 30 days, we could demonstrate: lack of necrosis and interstitial phlogosis and, especially in those animals treated with greater doses, numerical increase of peroxisomes, hypertrophy of SER and RER and a lesser regularity of glycogen distribution.
通过对大鼠肝脏进行组织学和电子显微镜研究,这些大鼠每日服用100毫克和200毫克替阿地诺,持续30天,我们可以证明:无坏死和间质炎症,尤其是在服用较大剂量药物的动物中,过氧化物酶体数量增加、滑面内质网和粗面内质网肥大以及糖原分布的规律性降低。