Enhanced adsorptive capacity of activated charcoal in the presence of magnesium citrate, N.F.

In a series of experiments to determine the effect of magnesium citrate solution, NF, on the adsorption of sodium salicylate onto charcoal, salicylate adsorption was shown to be enhanced in the presence of citrate ion and, to a lesser extent, magnesium ion. Additional in vitro and in vivo studies with sodium salicylate, as well as other drugs, will be necessary to fully assess the potential clinical implications of these findings.