Cohen M M, Simpson S J
Cytogenet Cell Genet. 1980;28(1-2):24-33. doi: 10.1159/000131508.
Growth rates were investigated in long-term lymphoblastoid cell lines derived from normal individuals and patients with ataxia telangiectasia (ATR). By a cell doubling method, sister chromatid exchanges, and autoradiography, the ATR cells showed a significantly longer total generation time. Autoradiography demonstrated that the difference in cell cycle was due to a specific lengthening of the S period in the ATR lymphoblasts.
对源自正常个体和共济失调毛细血管扩张症（ATR）患者的长期淋巴母细胞系的生长速率进行了研究。通过细胞倍增法、姐妹染色单体交换和放射自显影术，发现ATR细胞的总代时显著延长。放射自显影表明，细胞周期的差异是由于ATR淋巴母细胞中S期的特异性延长所致。
Zotero 插件