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家兔虹膜中两种去甲肾上腺素储存颗粒的生化证据。

Biochemical evidence for two types of noradrenaline storage particles in rabbit iris.

作者信息

De Potter W P, De Smet F H

出版信息

Experientia. 1980 Nov 15;36(11):1282-5. doi: 10.1007/BF01969589.

DOI:10.1007/BF01969589
PMID:7449914
Abstract

Centrifugation techniques were used to determine the subcellular distribution of noradrenaline (NA) and dopamine beta-hydroxylase (D beta H) in the rabbit iris. By application of isopycnic and differential gradient centrifugation methods 2 types of NA vesicles could be demonstrated. Of the total particle bound NA about 70% is associated with 'light' and about 30% with 'heavy' vesicles. For both types of vesicles the distribution of D beta H reflected that of NA.

摘要

采用离心技术测定去甲肾上腺素(NA)和多巴胺β-羟化酶(DβH)在兔虹膜中的亚细胞分布。通过等密度离心和差速梯度离心方法,可证明存在两种类型的NA囊泡。在与颗粒结合的总NA中,约70%与“轻”囊泡相关,约30%与“重”囊泡相关。对于这两种类型的囊泡,DβH的分布反映了NA的分布。

相似文献

1
Biochemical evidence for two types of noradrenaline storage particles in rabbit iris.家兔虹膜中两种去甲肾上腺素储存颗粒的生化证据。
Experientia. 1980 Nov 15;36(11):1282-5. doi: 10.1007/BF01969589.
2
The effect of colchicine treatment on the buoyant density of noradrenaline storage particles in the rabbit superior cervical ganglion.
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4
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Biochemical observations on the formation of small noradrenergic vesicles in the splenic nerve of the dog.关于犬脾神经中小去甲肾上腺素能小泡形成的生化观察。
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本文引用的文献

1
Evidence for the presence of noradrenaline in submicroscopic structures of adrenergic axons.肾上腺素能轴突亚显微结构中存在去甲肾上腺素的证据。
Nature. 1956 Jan 7;177(4497):44-5. doi: 10.1038/177044b0.
2
Light and heavy norepinephrine storage particles in the rat heart and in bovine splenic nerve.大鼠心脏和牛脾神经中的轻、重去甲肾上腺素储存颗粒。
J Pharmacol Exp Ther. 1968 Aug;162(2):203-12.
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The storage of endogenous noradrenaline in sympathetic nerve terminals.内源性去甲肾上腺素在交感神经末梢中的储存。
J Physiol. 1971 May;215(1):163-79. doi: 10.1113/jphysiol.1971.sp009463.
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Evidence for 2 types of noradrenaline storage particles in dog spleen.犬脾脏中两种去甲肾上腺素储存颗粒的证据。
Nature. 1970 Dec 19;228(5277):1203-4. doi: 10.1038/2281203a0.
5
Distribution of noradrenaline storing particles in peripheral adrenergic neurons as revealed by electron microscopy.通过电子显微镜揭示的外周肾上腺素能神经元中去甲肾上腺素储存颗粒的分布。
Acta Physiol Scand. 1969 Aug;76(4):427-40. doi: 10.1111/j.1748-1716.1969.tb04488.x.
6
[Localization of noradrenaline from a particular fraction isolated from rat iris treated with tritiated noradrenaline].[用氚标记去甲肾上腺素处理大鼠虹膜后,从分离出的特定组分中对去甲肾上腺素进行定位]
C R Acad Hebd Seances Acad Sci D. 1969 Mar 10;268(10):1445-7.
7
Evidence for the presence of dopamine- -hydroxylase in both populations of noradrenaline storage vesicles in sympathetic nerve terminals of the rat vas deferens.大鼠输精管交感神经末梢中去甲肾上腺素储存囊泡的两种群体中均存在多巴胺-β-羟化酶的证据。
J Neurochem. 1973 Jan;20(1):245-8. doi: 10.1111/j.1471-4159.1973.tb12122.x.
8
Subcellular localisation of noradrenaline in sympathetic neurons.去甲肾上腺素在交感神经元中的亚细胞定位。
Pharmacol Rev. 1972 Sep;24(3):435-57.
9
Facilitation of the release of noradrenaline and dopamine- -hydroxylase at low stimulation frequencies by -blocking agents.
Arch Int Pharmacodyn Ther. 1971 Sep;193(1):191-7.
10
Synaptic vesicles in sympathetic neurons.交感神经元中的突触小泡。
Physiol Rev. 1971 Jan;51(1):98-157. doi: 10.1152/physrev.1971.51.1.98.