Stroev E A, Kazakova N T
Farmakol Toksikol. 1980 Sep-Oct;43(5):601-3.
The effect of combined administration of flavin coenzymes and pyridoxine on B2-avitaminosis rats' supply with these vitamins has been studied. It has been disclosed that pyridoxine promotes more effective normalization of riboflavin and pyridoxine balance in the body, this balance being measured from the excretion of riboflavin and 4-pyridoxin acid with urine as well as from the content of total flavins in blood and tissues. In vitamin B2 lack, it is recommended that pyridoxin be combined with flavin mononucleotide and in particular with flavin adenine dinucleotide.
研究了黄素辅酶和吡哆醇联合给药对维生素B2缺乏症大鼠这些维生素供应的影响。结果表明,吡哆醇能更有效地促进体内核黄素和吡哆醇平衡的正常化,这种平衡是通过尿液中核黄素和4-吡哆醇酸的排泄以及血液和组织中总黄素的含量来衡量的。在维生素B2缺乏的情况下,建议将吡哆醇与黄素单核苷酸,特别是与黄素腺嘌呤二核苷酸联合使用。