吸烟与消化性溃疡的门诊内镜调查
Outpatient endoscopic survey of smoking and peptic ulcer.
作者信息
Ainley C C, Forgacs I C, Keeling P W, Thompson R P
出版信息
Gut. 1986 Jun;27(6):648-51. doi: 10.1136/gut.27.6.648.
Abstract
A survey of the smoking habits of 1217 outpatients undergoing upper gastrointestinal endoscopy was carried out over an 18 month period. Six hundred and twenty four were current smokers, 248 ex-smokers and 345 non-smokers. 11.9% of smokers had gastric ulcers, 7.7% of ex-smokers (p less than 0.025) and 4.6% of non-smokers (p less than 0.001). 2.8% of smokers had duodenal ulcers, 6.8% of ex-smokers (p less than 0.01) and 6.1% of non-smokers (p less than 0.001). There was a dose response effect between the number of cigarettes smoked and duodenal and gastric ulceration. Gastric cancer was also more frequent in smokers than non-smokers (p less than 0.01), but macroscopic oesophagitis less frequent (p less than 0.001). The results confirm the association between smoking and peptic ulcer.
摘要
在18个月的时间里，对1217名接受上消化道内镜检查的门诊患者的吸烟习惯进行了调查。其中624人是当前吸烟者，248人是既往吸烟者，345人是非吸烟者。11.9%的吸烟者患有胃溃疡，既往吸烟者为7.7%（p<0.025），非吸烟者为4.6%（p<0.001）。2.8%的吸烟者患有十二指肠溃疡，既往吸烟者为6.8%（p<0.01），非吸烟者为6.1%（p<0.001）。吸烟数量与十二指肠溃疡和胃溃疡之间存在剂量反应关系。吸烟者患胃癌的频率也高于非吸烟者（p<0.01），但肉眼可见的食管炎频率较低（p<0.001）。结果证实了吸烟与消化性溃疡之间的关联。
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本文引用的文献
1
Association between smoking and disease in men over sixty.60岁以上男性吸烟与疾病之间的关联。
Lancet. 1959 Jan 24;1(7065):196-200. doi: 10.1016/s0140-6736(59)90385-x.
2
Effect of smoking on the production and maintenance of gastric and duodenal ulcers.吸烟对胃和十二指肠溃疡形成及维持的影响。
Lancet. 1958 Mar 29;1(7022):657-62. doi: 10.1016/s0140-6736(58)91083-3.
3
Computer-assisted electrocoagulation: bipolar vs. monopolar in the treatment of experimental canine gastric ulcer bleeding.计算机辅助电凝术：双极与单极在实验性犬胃溃疡出血治疗中的应用
Gastroenterology. 1981 Mar;80(3):451-5.
4
Factors affecting the healing rate of duodenal and pyloric ulcers with low-dose antacid treatment.低剂量抗酸剂治疗十二指肠溃疡和幽门溃疡时影响愈合率的因素。
Gut. 1981 Feb;22(2):97-102. doi: 10.1136/gut.22.2.97.
5
Environmental factors and chronic gastric ulcer. A case control study of the association of smoking, alcohol, and heavy analgesic ingestion with the exacerbation of chronic gastric ulcer.环境因素与慢性胃溃疡。一项关于吸烟、饮酒和大量服用镇痛药与慢性胃溃疡病情加重之间关联的病例对照研究。
Scand J Gastroenterol. 1982 Sep;17(6):721-9. doi: 10.3109/00365528209181085.
6
Cimetidine, cigarette smoking, and recurrence of duodenal ulcer.西咪替丁、吸烟与十二指肠溃疡复发
N Engl J Med. 1984 Sep 13;311(11):689-93. doi: 10.1056/NEJM198409133111101.
7
Recurrent ulcer after successful treatment with cimetidine or antacid.西咪替丁或抗酸剂成功治疗后复发性溃疡。
Gastroenterology. 1983 Oct;85(4):875-80.
8
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9
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