一名患有黄嘌呤尿症的女性连续两次怀孕：血清尿酸水平意外升高。

Two successive pregnancies in a woman with xanthinuria: unexpected increase in serum uric acid levels.

作者信息

Uzan S, Beaufils M, Ragot J, Brault D, Donsimoni R

出版信息

J Perinat Med. 1980;8(6):284-7. doi: 10.1515/jpme.1980.8.6.284.

DOI:10.1515/jpme.1980.8.6.284

Abstract

Two successive pregnancies were observed in a patient with xanthinuria. In each of them, maternal serum uric acid (SUA) level rose progressively during the third trimester, reaching a subnormal value just before delivery. The level of UA was slightly higher in arterial cord blood than in maternal blood. There was no difference between levels in arterial and venous cord blood. It is suggested that xanthine oxydase may be present in the placenta.

摘要

在一名患有黄嘌呤尿症的患者中观察到连续两次怀孕。在每次怀孕中，孕妇血清尿酸（SUA）水平在孕晚期逐渐升高，在分娩前达到低于正常的值。动脉脐血中的尿酸水平略高于母血中的尿酸水平。动脉脐血和静脉脐血中的尿酸水平没有差异。提示胎盘可能存在黄嘌呤氧化酶。