Frederick F J, Stewart I F, Worth A J
J Otolaryngol. 1980 Oct;9(5):423-8.
A case of giant cell lesion arising from the maxilla is presented. The final clinical and pathological interpretation was of a true giant cell tumor. A review of the literature reveals giant cell lesions of the maxilla to be rare, with the dominant interpretation being giant cell reparative granuloma. On rare occasions, these lesions have been reported as true giant cell tumors. The histogenesis of these lesions in unknown. They may arise from cells of undifferentiated connective tissue, bone marrow, or from abnormal hyperplasia of osteoclasts. The modality of treatment and prognosis is dependent upon the final diagnosis.
本文报告一例起源于上颌骨的巨细胞病变。最终临床及病理诊断为真性巨细胞瘤。文献回顾显示,上颌骨巨细胞病变较为罕见,主流诊断为巨细胞修复性肉芽肿。极少数情况下,这些病变被报告为真性巨细胞瘤。这些病变的组织发生尚不明确。它们可能起源于未分化结缔组织细胞、骨髓,或破骨细胞的异常增生。治疗方式及预后取决于最终诊断。