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Hematin therapy in porphyric attacks.

作者信息

Pierach C A, Bossenmaier I, Cardinal R, Weimer M, Watson C J

出版信息

Klin Wochenschr. 1980 Aug 15;58(16):829-32. doi: 10.1007/BF01491103.

DOI:10.1007/BF01491103
PMID:7453089
Abstract

We report our experience with hematin in the treatment of 57 patients in porphyric attacks. The ratio of acute intermittent porphyria: variegate porphyria: hereditary coproporphyria was 43:11:3. More than 90% of the patients showed not only a decline in their porphyrin precursors, but also a favor able clinical response. Hematin was well tolerated and should be considered the treatment of choice in porphyric relapse.

摘要

相似文献

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Hematin therapy in porphyric attacks.
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[Hematin treatment of acute intermittent porphyria. A case report (author's transl)].[急性间歇性卟啉病的血红素治疗。病例报告（作者译）]
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本文引用的文献

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The synthesis of enzymes concerned in bacteriochlorophyll formation in growing cultures of Rhodopseudomonas spheroides.球形红假单胞菌生长培养物中与细菌叶绿素形成相关的酶的合成。
J Gen Microbiol. 1960 Dec;23:487-98. doi: 10.1099/00221287-23-3-487.
2
Effects of hematin in hepatic porphyria. Further studies.血晶素对肝性卟啉症的影响。进一步研究。
Ann Intern Med. 1975 Jul;83(1):20-30. doi: 10.7326/0003-4819-83-1-20.
3
Comparison of the Hoesch and the Watson-Schwartz tests for urinary porphobilinogen.用于检测尿卟胆原的赫施试验与沃森-施瓦茨试验的比较。
Blood. 2023 Nov 9;142(19):1589-1599. doi: 10.1182/blood.2022018662.
4
Therapy Follows Diagnosis: Old and New Approaches for the Treatment of Acute Porphyrias, What We Know and What We Should Know.治疗遵循诊断：急性卟啉病治疗的新旧方法，我们所知道的和我们应该知道的。
Diagnostics (Basel). 2022 Jul 3;12(7):1618. doi: 10.3390/diagnostics12071618.
5
The "glucose effect" in acute hepatic porphyrias and in experimental porphyria.急性肝卟啉病及实验性卟啉病中的“葡萄糖效应”
Klin Wochenschr. 1981 Jul 1;59(13):727-35. doi: 10.1007/BF01721260.
6
Prevention of neonatal hyperbilirubinemia by tin protoporphyrin IX, a potent competitive inhibitor of heme oxidation.锡原卟啉IX预防新生儿高胆红素血症，锡原卟啉IX是血红素氧化的一种有效竞争性抑制剂。
Proc Natl Acad Sci U S A. 1981 Oct;78(10):6466-70. doi: 10.1073/pnas.78.10.6466.
7
Pharmacokinetics of intravenously administered haem arginate.静脉注射血红素精氨酸盐的药代动力学
Br J Clin Pharmacol. 1986 Sep;22(3):331-5. doi: 10.1111/j.1365-2125.1986.tb02895.x.
Clin Chem. 1977 Sep;23(9):1666-8.
4
Incorporation of exogenous heme into hepatic cytochrome P-450 in vivo.体内外源性血红素掺入肝细胞色素P-450。
J Biol Chem. 1979 Jan 10;254(1):15-7.
5
Transitory renal failure following rapid administration of a relatively large amount of hematin in a patient with acute intermittent porphyria in clinical remission.在临床缓解期的急性间歇性卟啉症患者中，快速给予相对大量的氯高铁血红素后出现的短暂性肾衰竭。
Acta Med Scand. 1978;203(5):437-43. doi: 10.1111/j.0954-6820.1978.tb14903.x.
6
[Hematin treatment of acute intermittent porphyria. A case report (author's transl)].[急性间歇性卟啉病的血红素治疗。病例报告（作者译）]
Rev Bras Pesqui Med Biol. 1979 Sep;12(4-5):325-33.
7
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Eur Neurol. 1979;18(5):289-94. doi: 10.1159/000115092.
8
New type of hepatic porphyria with porphobilinogen synthase defect and intermittent acute clinical manifestation.一种新型肝性卟啉病，伴有胆色素原合酶缺陷及间歇性急性临床表现。
Klin Wochenschr. 1979 Oct 15;57(20):1123-7. doi: 10.1007/BF01481493.
9
[Effect of hematin in acute porphyric relapse].[血红素对急性卟啉症复发的影响]
Rev Med Chil. 1979 Jan;107(1):38-41.
10
Hematin therapy for acute porphyria.急性卟啉病的血红素疗法。
Medicine (Baltimore). 1979 May;58(3):252-69. doi: 10.1097/00005792-197905000-00005.