Pierach C A, Cardinal R, Bossenmaier I, Watson C J
Clin Chem. 1977 Sep;23(9):1666-8.
A comparison of the Hoesch and the Watson-Schwartz tests shows that the latter, although slightly more complicated, generally yields more concise results and is superior in sensitivity and specificity for porphobilinogen. The recommendation of the Hoesch test for use as a "bedside screening" method seems unrealistic. Before the diagnosis of an "inducible" porphyria is made, a positive Hoesch test requires that indoles, indoleacetic acid, methyldopa, end-stage alcoholic malnutrition, and phenazopyridine HCl be excluded, to avoid misinterpretation.
霍施试验与沃森 - 施瓦茨试验的比较表明，后者虽然稍复杂一些，但通常能产生更简洁的结果，并且在对卟啉胆原的敏感性和特异性方面更具优势。将霍施试验推荐用作“床边筛查”方法似乎不切实际。在做出“可诱导性”卟啉症的诊断之前，霍施试验呈阳性时需要排除吲哚、吲哚乙酸、甲基多巴、终末期酒精性营养不良以及盐酸非那吡啶，以避免误诊。
