Hawkins D B, Luxford W M
Laryngoscope. 1980 Dec;90(12):1921-6. doi: 10.1288/00005537-198012000-00001.
Schwannomas are relatively rare tumors that arise from Schwann cells of the sheaths of peripheral nerves. They may be found in any portion of the body. In reported series of schwannomas, the percentage of tumors in the head and neck varies from 16% to 45%. Usually demonstrating slow growth, they often have a history of long duration, and are most often diagnosed in adults. Approximately 10% of schwannomas are diagnosed in patients under 21 years of age. In this paper two children with large schwannomas of the head and neck are reported. In both, the symptoms were of relatively short duration, but physical findings suggested that the tumors had been present much longer. One patient was a 10-year-old female with a schwannoma filling the anterior and posterior triangles of the left side of her neck and extending superiorly to the base of the skull. The tumor intimately involved the vagus, spinal accessory, and hypoglossal nerves. The other patient was a 12-year-old female with a nasal tumor filling the right naris and nasopharynx. Our management of these patients is discussed.
神经鞘瘤是相对罕见的肿瘤，起源于周围神经鞘的施万细胞。它们可出现在身体的任何部位。在已报道的神经鞘瘤系列病例中，头颈部肿瘤的比例在16%至45%之间。神经鞘瘤通常生长缓慢，病史往往较长，最常见于成年人。约10%的神经鞘瘤在21岁以下的患者中被诊断出来。本文报道了两名患有头颈部大型神经鞘瘤的儿童。在这两名患者中，症状持续时间相对较短，但体格检查结果提示肿瘤已经存在了更长时间。一名患者是一名10岁女性，其神经鞘瘤占据了左侧颈部的前后三角区，并向上延伸至颅底。肿瘤紧密累及迷走神经、副神经和舌下神经。另一名患者是一名12岁女性，其鼻腔肿瘤占据了右侧鼻孔和鼻咽部。本文讨论了我们对这些患者的治疗方法。
