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头颈部罕见神经鞘瘤 2 例。

Two rare schwannomas of head and neck.

机构信息

Department of Pathology, Hassan II University Hospital of Fez, Hassan, Morocco.

出版信息

Diagn Pathol. 2014 Feb 5;9:27. doi: 10.1186/1746-1596-9-27.

Abstract

UNLABELLED

Twenty-five to 45 percent of all schwannomas occur in the head and neck. Most of them arise along the vestibular portion of the eighth cranial nerve (acoustic neurinoma). They rarely originate from the peripheral facial nerve or other nerves within the parotid gland. Less than 4% of schwannomas involve the nasal cavity and paranasal sinuses. They arise from the branches of the trigeminal nerve and autonomic nervous system.We report two cases of schwannomas arisng from intraparotid facial nerve and nasal cavity. The first case diagnosed in a 62-year-old-man presented with 2-year-history of painless mass of the parotid gland. The lesion was found to be cystic through the pre operative examinations and investigations. The histology of the specimen retained an intraparotid cystic schwannoma. The second case concerned a 75-year-old-man presented with episodes of nasal obstruction, rhinorrhea, anosmia and headache. Histological study of the specimen showed fusiform cells with strongly and diffusely immunostaining for S100 protein suggesting a schwannoma.

VIRTUAL SLIDES

http://www.diagnosticpathology.diagnomx.eu/vs/1098335216112242.

摘要

未注明

所有神经鞘瘤的 25%至 45%发生在头部和颈部。它们大多起源于第八颅神经(听神经瘤)的前庭部分。它们很少起源于周围面神经或腮腺内的其他神经。少于 4%的神经鞘瘤涉及鼻腔和鼻旁窦。它们起源于三叉神经和自主神经系统的分支。我们报告了两例起源于腮腺内面神经和鼻腔的神经鞘瘤。第一个病例诊断为 62 岁男性,有 2 年的腮腺无痛性肿块史。术前检查和检查发现病变为囊性。标本的组织学保留了腮腺内囊性神经鞘瘤。第二个病例涉及一名 75 岁男性,表现为间歇性鼻塞、流涕、嗅觉丧失和头痛。标本的组织学研究显示梭形细胞,S100 蛋白强烈弥漫免疫染色提示神经鞘瘤。

虚拟幻灯片

http://www.diagnosticpathology.diagnomx.eu/vs/1098335216112242.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dbbc/3996150/b7c5397d43e2/1746-1596-9-27-1.jpg

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