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暴露于诊断超声后培养细胞表面特征的形态学变化。

Morphological changes in the surface characteristics of cultured cells after exposure to diagnostic ultrasound.

作者信息

Liebeskind D, Bases R, Koenigsberg M, Koss L, Raventos C

出版信息

Radiology. 1981 Feb;138(2):419-23. doi: 10.1148/radiology.138.2.7455124.

DOI:10.1148/radiology.138.2.7455124
PMID:7455124
Abstract

Morphological changes in the surface membranes of cultured Balb/c 3T3, clone 1-13 cells were studied by scanning electron microscopy after the cells were exposed to diagnostic ultrasound. Abundant irregular, dense microvilli appeared in transformed clones as well as in cells that had been exposed to ultrasound, but had not been morphologically transformed. This increased density of microvilli was detected as early as three days after ultrasound and was still present 37 days later. In comparison, unexposed control cells were smooth with occasional microvilli. Further studies are needed of the effects of diagnostic ultrasound.

摘要

在将培养的Balb/c 3T3克隆1-13细胞暴露于诊断超声后,通过扫描电子显微镜研究了其表面膜的形态变化。在转化的克隆以及暴露于超声但未发生形态转化的细胞中出现了大量不规则的密集微绒毛。微绒毛密度的增加早在超声处理后三天就被检测到,并且在37天后仍然存在。相比之下,未暴露的对照细胞表面光滑,偶尔有微绒毛。需要进一步研究诊断超声的影响。

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Br J Cancer Suppl. 1982 Mar;5:176-86.