对青霉素过敏。“体内”和“体外”试验的比较。

Allergy to penicillin. Comparison of "in vivo" and "in vitro" tests.

作者信息

Olivé A, Huguet J, Vich J M, García-Calderón J V, García-Calderón P A

出版信息

Allergol Immunopathol (Madr). 1980 Mar-Apr;8(2):105-10.

Abstract

Skin tests (SKT) and Lymphocyte Transformation Test (LTT) utilizing sodium penicillin G (PNG) and penicilloyl polylysine (PPL) and Rast to penicilloyl G were carried out on forty patients with a history of allergic reactions to penicillin, the results obtained indicated no statistically significant difference between the use of SKT or LTT in the diagnosis of allergy to penicillin (X2, p > 0,05), while the use of Rast showed a statistically significant difference (X2, p < 0,001) in favour of LTT and SKT. The use of either type of allergen (PNG or PPL) in LTT or SKT showed a significant difference in favour of the former (X2, p < 0,01).

摘要

对40例有青霉素过敏反应史的患者进行了皮肤试验（SKT）、利用青霉素G钠（PNG）和青霉噻唑聚赖氨酸（PPL）的淋巴细胞转化试验（LTT）以及对青霉噻唑G的放射变应原吸附试验（RAST）。所得结果表明，在青霉素过敏诊断中使用SKT或LTT之间无统计学显著差异（X²，p＞0.05），而使用RAST则显示出有利于LTT和SKT的统计学显著差异（X²，p＜0.001）。在LTT或SKT中使用任何一种变应原（PNG或PPL）均显示出有利于前者的显著差异（X²，p＜0.01）。