Wittmers L E, Alich A, Aufderheide A C
Am J Clin Pathol. 1981 Jan;75(1):80-5. doi: 10.1093/ajcp/75.1.80.
A method for direct lead content analysis of milligram quantities of bone ash by flameless atomic absorption spectroscopy is described. Bone ash (25 mg) is dissolved with HNO3 and diluted with H2O and La2O3 (1,000 micrograms/ml) solution. Lanthanum ion is used to suppress matrix interferences possibly arising in part from sulfate components of the bone ash. Two bulk bone samples (about 14 and 60 micrograms Pb/g ash, respectively) were used to determine daily, within-day, and overall variability of the method. Values for "low lead" bone samples were 14.08 +/- 1.74 (SD) microgram Pb/g ash and for "high lead" bone samples were 60.85 +/- 5.24 (SD) microgram Pb/b ash. The overall value of 58 lead recovery determinations from bone ash analysis was 103.5% (+/- 12.9% SD). These values compare favorably with results previously reported using gram amounts of sample.
描述了一种通过无火焰原子吸收光谱法直接分析毫克量骨灰中铅含量的方法。将骨灰（25毫克）用硝酸溶解，并用去离子水和氧化镧（1000微克/毫升）溶液稀释。镧离子用于抑制可能部分源于骨灰中硫酸盐成分的基体干扰。使用两个大量骨样品（分别约为14和60微克铅/克骨灰）来确定该方法的每日、日内和总体变异性。“低铅”骨样品的值为14.08±1.74（标准差）微克铅/克骨灰，“高铅”骨样品的值为60.85±5.24（标准差）微克铅/克骨灰。骨灰分析中58次铅回收率测定的总体值为103.5%（±12.9%标准差）。这些值与先前使用克量样品报道的结果相比具有优势。
