Caillé J M, Billerey J, Renou A M, Constant P
Neuroradiology. 1978;16:579-82. doi: 10.1007/BF00395368.
The attenuation coefficients of cerebral parenchyma and systemic blood were simultaneously measured at varying times after injection of two contrast agents with differing osmolarities. Cerebral parenchyma was in fact denser than the theory would predict. The osmolarity of the iodinated contrast agents seems to play only a very minor part. However, liposolubility could perhaps explain the leakage of iodine across the BBB and thus the increase in the attenuation coefficient of cerebral parenchyma.
在注射两种不同渗透压的造影剂后的不同时间，同时测量脑实质和全身血液的衰减系数。实际上，脑实质比理论预测的密度更高。碘化造影剂的渗透压似乎只起很小的作用。然而，脂溶性或许可以解释碘透过血脑屏障的渗漏情况，进而解释脑实质衰减系数的增加。
