Abramov L N, Merkulova L M
Arkh Anat Gistol Embriol. 1980 Nov;79(11):66-71.
Histotopography and activity of true and false cholinesterases in the non-inbred white rat hearts, normal and at the effect of pulsed electromagnetic field (80 kA/m) have been demonstrated by Karnovsky-Roots histochemical method. It has been stated that a single 6 hours' application of the pulsed electromagnetic field results in an increased cholinesterase activity in all cardiac structures, besides neurocytes. If the application is continued, cholinesterase activity is progressively decreasing and its minimum is observed on the 10th day of the stimulation. From the 15th day on, increasing enzymatic activities are observed, various for different enzymes: that of acetylcholinesterase even by the 30th day of the stimulation by the magnetic field does not reach the normal level, while that of cholinesterase exceeds this level. Mast cells are noted to appear along the cholinergic neural fibres. A suggestion is made on possible exchange between them by mediator acetylcholine. Electrocardiographic data have demonstrated that certain correlation exists between acetylcholinesterase activity and the cardiac function.
采用卡诺夫斯基-罗茨组织化学方法，已证实非近交系白色大鼠心脏中真性和假性胆碱酯酶的组织定位及活性，包括正常心脏以及受脉冲电磁场（80 kA/m）作用后的心脏。研究表明，单次施加6小时的脉冲电磁场会使除神经细胞外的所有心脏结构中的胆碱酯酶活性增加。如果持续施加，胆碱酯酶活性会逐渐降低，并在刺激的第10天观察到其最低值。从第15天起，观察到酶活性增加，不同酶的情况各异：磁场刺激至第30天时，乙酰胆碱酯酶的活性仍未达到正常水平，而胆碱酯酶的活性则超过了该水平。注意到肥大细胞沿胆碱能神经纤维出现。有人提出它们之间可能通过介质乙酰胆碱进行交换。心电图数据表明，乙酰胆碱酯酶活性与心脏功能之间存在一定相关性。
