Binder P S, Rasmussen D M, Gordon M
Arch Ophthalmol. 1981 Jan;99(1):87-90. doi: 10.1001/archopht.1981.03930010089009.
Three patients with soft contact lenses had acute onset of a red eye that clinically appeared consistent with an adenoviral keratoconjunctivitis. The signs and symptoms cleared within five to ten days in all three patients. When the patients reinserted their lenses after their initial episodes, the same signs and symptoms again developed, including follicular conjunctivitis, punctate keratitis, and subepithelial infiltrates. All three were using preserved solutions for soft lens disinfection, and when switched to thermal disinfection with saline tablets, a recurrence of the syndrome did not develop when the lenses were replaced. This syndrome seems related to a toxic or allergic reaction to the preservatives in the contact lens disinfecting solutions. Similar patients who have an acute or chronic, red, irritated eye should stop their lens wear and later should change their disinfection technique to one that uses unpreserved saline solution to eliminate the problem.
三名佩戴软性隐形眼镜的患者突然出现眼红，临床症状与腺病毒性角结膜炎相符。三名患者的体征和症状均在五至十天内消退。当这些患者在初次发病后重新佩戴隐形眼镜时，同样的体征和症状再次出现，包括滤泡性结膜炎、点状角膜炎和上皮下浸润。这三名患者均使用含防腐剂的溶液进行软性隐形眼镜消毒，当改用盐片进行热消毒时，更换镜片后综合征未复发。这种综合征似乎与隐形眼镜消毒溶液中的防腐剂的毒性或过敏反应有关。有急性或慢性眼红、眼不适的类似患者应停止佩戴隐形眼镜，之后应将消毒技术改为使用无防腐剂的盐溶液以解决问题。
