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Chloroform-induced glutathione depletion and toxicity in freshly isolated hepatocytes.

作者信息

Ekström T, Högberg J

出版信息

Biochem Pharmacol. 1980 Nov 15;29(22):3059-65. doi: 10.1016/0006-2952(80)90446-3.

DOI:10.1016/0006-2952(80)90446-3

PMID:7458959

Abstract

摘要

相似文献

Chloroform-induced glutathione depletion and toxicity in freshly isolated hepatocytes.

Biochem Pharmacol. 1980 Nov 15;29(22):3059-65. doi: 10.1016/0006-2952(80)90446-3.

Carbon tetrachloride-mediated expiration of pentane and chloroform by the intact rat: the effects of pretreatment with diethyl maleate, SKF-525A and phenobarbital.

Toxicol Lett. 1982 Apr;11(1-2):165-71. doi: 10.1016/0378-4274(82)90123-0.

Metabolism of toxic substances in isolated hepatocytes.

Toxicology. 1980;17(2):113-8. doi: 10.1016/0300-483x(80)90082-7.

The role of glutathione in chloroform-induced hepatotoxicity.

Exp Mol Pathol. 1976 Feb;24(1):13-22. doi: 10.1016/0014-4800(76)90053-8.

Chloroform-induced cytolethality in freshly isolated male B6C3F1 mouse and F-344 rat hepatocytes.

Toxicol Appl Pharmacol. 1998 Apr;149(2):217-25. doi: 10.1006/taap.1997.8351.

Mechanisms of chloroform-induced hepatotoxicity: oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes.

J Toxicol Environ Health A. 2007 Nov;70(22):1936-45. doi: 10.1080/15287390701551399.

The mechanism of prevention of paracetamol-induced hepatotoxicity by 3,5-dialkyl substitution. The roles of glutathione depletion and oxidative stress.

Biochem Pharmacol. 1987 Jul 1;36(13):2065-70. doi: 10.1016/0006-2952(87)90132-8.

The effect of protein deficiency and microsomal enzyme induction by DDT and phenobarbitone on the acute toxicity of chloroform and a pyrrolizidine alkaloid, retrorsine.

Br J Exp Pathol. 1970 Jun;51(3):317-21.

Is chemiluminescence an index of hepatic lipoperoxidation accompanying chloroform anesthesia?

Biochim Biophys Acta. 1986 Dec 10;884(3):517-9. doi: 10.1016/0304-4165(86)90203-5.

[Potentiation and inhibition of chloroform liver toxicity by drugs].

Anaesthesist. 1971 Apr;20(4):149-50.

引用本文的文献

An Adverse Outcome Pathway Linking Organohalogen Exposure to Mitochondrial Disease.

J Toxicol. 2019 Apr 1;2019:9246495. doi: 10.1155/2019/9246495. eCollection 2019.

Iron loading of cultured hepatocytes. Effect of iron on 5-aminolaevulinate synthase is independent of lipid peroxidation.

Biochem J. 1983 May 15;212(2):321-30. doi: 10.1042/bj2120321.

Inhibition of microsomal lipid peroxidation by glutathione and glutathione transferases B and AA. Role of endogenous phospholipase A2.

Biochem J. 1984 May 15;220(1):243-52. doi: 10.1042/bj2200243.

Hepatotoxic interaction between carbon tetrachloride and chloroform in ethanol treated rats.

Arch Toxicol. 1992;66(8):580-6. doi: 10.1007/BF01973389.

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Chloroform-induced glutathione depletion and toxicity in freshly isolated hepatocytes.

作者信息

Ekström T, Högberg J

出版信息

Biochem Pharmacol. 1980 Nov 15;29(22):3059-65. doi: 10.1016/0006-2952(80)90446-3.

DOI:10.1016/0006-2952(80)90446-3

PMID:7458959

Abstract

摘要

相似文献

Chloroform-induced glutathione depletion and toxicity in freshly isolated hepatocytes.

Biochem Pharmacol. 1980 Nov 15;29(22):3059-65. doi: 10.1016/0006-2952(80)90446-3.

Carbon tetrachloride-mediated expiration of pentane and chloroform by the intact rat: the effects of pretreatment with diethyl maleate, SKF-525A and phenobarbital.

Toxicol Lett. 1982 Apr;11(1-2):165-71. doi: 10.1016/0378-4274(82)90123-0.

Metabolism of toxic substances in isolated hepatocytes.

Toxicology. 1980;17(2):113-8. doi: 10.1016/0300-483x(80)90082-7.

The role of glutathione in chloroform-induced hepatotoxicity.

Exp Mol Pathol. 1976 Feb;24(1):13-22. doi: 10.1016/0014-4800(76)90053-8.

Chloroform-induced cytolethality in freshly isolated male B6C3F1 mouse and F-344 rat hepatocytes.

Toxicol Appl Pharmacol. 1998 Apr;149(2):217-25. doi: 10.1006/taap.1997.8351.

Mechanisms of chloroform-induced hepatotoxicity: oxidative stress and mitochondrial permeability transition in freshly isolated mouse hepatocytes.

J Toxicol Environ Health A. 2007 Nov;70(22):1936-45. doi: 10.1080/15287390701551399.

The mechanism of prevention of paracetamol-induced hepatotoxicity by 3,5-dialkyl substitution. The roles of glutathione depletion and oxidative stress.

Biochem Pharmacol. 1987 Jul 1;36(13):2065-70. doi: 10.1016/0006-2952(87)90132-8.

The effect of protein deficiency and microsomal enzyme induction by DDT and phenobarbitone on the acute toxicity of chloroform and a pyrrolizidine alkaloid, retrorsine.

Br J Exp Pathol. 1970 Jun;51(3):317-21.

Is chemiluminescence an index of hepatic lipoperoxidation accompanying chloroform anesthesia?

Biochim Biophys Acta. 1986 Dec 10;884(3):517-9. doi: 10.1016/0304-4165(86)90203-5.

[Potentiation and inhibition of chloroform liver toxicity by drugs].

Anaesthesist. 1971 Apr;20(4):149-50.

引用本文的文献

An Adverse Outcome Pathway Linking Organohalogen Exposure to Mitochondrial Disease.

J Toxicol. 2019 Apr 1;2019:9246495. doi: 10.1155/2019/9246495. eCollection 2019.

Iron loading of cultured hepatocytes. Effect of iron on 5-aminolaevulinate synthase is independent of lipid peroxidation.

Biochem J. 1983 May 15;212(2):321-30. doi: 10.1042/bj2120321.

Inhibition of microsomal lipid peroxidation by glutathione and glutathione transferases B and AA. Role of endogenous phospholipase A2.

Biochem J. 1984 May 15;220(1):243-52. doi: 10.1042/bj2200243.

Hepatotoxic interaction between carbon tetrachloride and chloroform in ethanol treated rats.

Arch Toxicol. 1992;66(8):580-6. doi: 10.1007/BF01973389.