Boyce J F, Schürch S, McIver D J
Atherosclerosis. 1980 Nov;37(3):361-70. doi: 10.1016/0021-9150(80)90140-9.
Interfacial tensions at the saline/arterial wall interface were determined by measuring contact angles between various test fluid droplets and the walls of rabbit aortae immersed in physiological saline. These contact angles and the interfacial tensions of the test fluid/bathing fluid interface (measured by the Du Noüy ring method) were converted to saline/arterial wall interfacial tensions by applying Neumann's equation of state. Four diseased animals, fed an atherogenic diet for 6-8 weeks and 6 controls formed the experimental group. A significantly higher interfacial tension (P < 0.001), was determined for lesion surfaces in atherosclerotic arteries (0.36 +/- 0.08 (SEM) mM . M-1, n = 13) compared to both the surrounding undisturbed regions (0.035 +/- 0.01 mN . m-1, n = 14) and the intact surface of control vessels (0.060 +/- mN . m-1, n = 48). This increase may reflect a change in the strength of hydrophilic interactions associated with the lesion surface in atherogenesis.
通过测量各种测试液滴与浸于生理盐水中的兔主动脉壁之间的接触角，来测定盐水/动脉壁界面处的界面张力。通过应用诺伊曼状态方程，将这些接触角以及测试液/浴液界面的界面张力（用杜诺伊环法测量）换算为盐水/动脉壁界面张力。四只因喂食致动脉粥样化饮食6至8周而患病的动物以及六只对照动物构成了实验组。与周围未受干扰区域（0.035±0.01毫牛顿/米，n = 14）和对照血管的完整表面（0.060±毫牛顿/米，n = 48）相比，动脉粥样硬化动脉病变表面的界面张力显著更高（P < 0.001）（0.36±0.08（标准误）毫摩尔·米⁻¹，n = 13）。这种增加可能反映了动脉粥样硬化形成过程中与病变表面相关的亲水相互作用强度的变化。
