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[冷加压试验期间正常人和高血压患者的血小板聚集情况]

[Platelet aggregation in normal and hypertensive subjects during cold pressor test].

作者信息

Saitta A, Trifiletti A, Mangano C, Coglitore G, Barberi I, Pizzoleo M A, Scamardi R, Squadrito G

出版信息

Boll Soc Ital Biol Sper. 1980 Aug 15;56(15):1553-9.

PMID:7459074
Abstract

The Authors have studied, in 5 normal subjects and in 10 with essential arterial hypertension, the behaviour of platelet aggregation before, during and after cold pressor test. It has been possible to evidence, in hypertensive subjects, a greater responsiveness of platelets to adrenaline induced aggregation. The Authors think that such effects may be due to hyperexcitability of sympathetic nervous system, which can regulate the functional behaviour of platelets in response to cold pressor test.

摘要

作者对5名正常受试者和10名原发性动脉高血压患者进行了研究,观察了冷加压试验前、试验期间及试验后的血小板聚集情况。已证实,高血压患者的血小板对肾上腺素诱导的聚集反应性更高。作者认为,这种效应可能是由于交感神经系统过度兴奋所致,交感神经系统可调节血小板在冷加压试验中的功能行为。

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