前负荷降低后收缩期时间间期变化与左心室舒张末期直径之间的相关性。药物干预的无创监测。
Correlation between changes in systolic time intervals and left ventricular end-diastolic diameter after preload reduction. Non-invasive monitoring of pharmacological intervention.
作者信息
Buch J, Egeblad H, Hansen P B, Kjaergård H, Waldorff S, Steiness E
出版信息
Br Heart J. 1980 Dec;44(6):668-71. doi: 10.1136/hrt.44.6.668.
Abstract
In order to measure the effect of a decrease in preload on systolic time intervals and left ventricular end-diastolic diameter (LVEDD) measured by echocardiography, eight healthy young subjects were given 40 mg frusemide intravenously. The pre-ejection period index (PEPI) increased and the left ventricular end-diastolic diameter decreased. A correlation between delta PEPI and delta LVEDD was shown. Using changes in systolic time intervals in the evaluation of changes in contractility it is important to correct for changes in preload. For normal subjects it is suggested that the relation between delta PEPI and delta LVEDD as a percentage of the mean values should be used for this correction. A method is suggested for estimating the changes in pre-ejection period index induced by changes in left ventricular end-diastolic diameter.
摘要
为了测量前负荷降低对通过超声心动图测量的收缩期时间间期和左心室舒张末期直径（LVEDD）的影响，对8名健康年轻受试者静脉注射40毫克速尿。射血前期指数（PEPI）增加，左心室舒张末期直径减小。显示了ΔPEPI与ΔLVEDD之间的相关性。在评估心肌收缩力变化时使用收缩期时间间期的变化，校正前负荷的变化很重要。对于正常受试者，建议使用ΔPEPI与ΔLVEDD相对于平均值的百分比之间的关系进行这种校正。提出了一种估计左心室舒张末期直径变化引起的射血前期指数变化的方法。
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