• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Effects of fasting on the composition of gallbladder bile.禁食对胆囊胆汁成分的影响。
Gut. 1980 Dec;21(12):1087-9. doi: 10.1136/gut.21.12.1087.
2
Effects of fasting on bile acid metabolism and biliary lipid composition in man.禁食对人体胆汁酸代谢和胆汁脂质成分的影响。
J Lipid Res. 1976 May;17(3):211-9.
3
Effect of primary bile acid ingestion on bile acid metabolism and biliary lipid secretion in gallstone patients.原发性胆汁酸摄入对胆结石患者胆汁酸代谢及胆汁脂质分泌的影响。
Gastroenterology. 1975 Dec;69(6):1301-14.
4
Role of gallbladder in gallstone formation.胆囊在胆结石形成中的作用。
Acta Chir Scand. 1974;140(1):45-9.
5
Effect of biliary obstruction on canine plasma and biliary lipids.胆管梗阻对犬血浆和胆汁脂质的影响。
Lipids. 1973 Sep;8(9):522-30. doi: 10.1007/BF02531988.
6
The effect of vagotomy on biliary secretions and bile salt pools in dogs.迷走神经切断术对犬胆汁分泌及胆盐池的影响。
Ann Surg. 1974 Apr;179(4):406-11. doi: 10.1097/00000658-197404000-00004.
7
Biliary lipid output during three meals and an overnight fast. I. Relationship to bile acid pool size and cholesterol saturation of bile in gallstone and control subjects.三餐及夜间禁食期间的胆汁脂质输出。I. 胆结石患者与对照受试者中胆汁脂质输出与胆汁酸池大小及胆汁胆固醇饱和度的关系。
Gut. 1975 Jan;16(1):1-11. doi: 10.1136/gut.16.1.1.
8
Biliary lipid output during three meals and an overnight fast. II. Effect of chenodeoxycholic acid treatment in gallstone subjects.三餐及夜间禁食期间的胆汁脂质排出量。II. 鹅去氧胆酸治疗对胆结石患者的影响。
Gut. 1975 Jan;16(1):12-7. doi: 10.1136/gut.16.1.12.
9
Biliary lipid metabolism in the pregnant baboon.妊娠狒狒的胆汁脂质代谢
Surg Gynecol Obstet. 1977 May;144(5):727-33.
10
Increased sulfation of lithocholate in patients with cholesterol gallstones during chenodeoxycholate treatment.鹅去氧胆酸治疗期间胆固醇结石患者中石胆酸硫酸化增加。
Digestion. 1975;12(2):105-10. doi: 10.1159/000197660.

引用本文的文献

1
Non-linear relationship between the first meal time of the day and gallstone incidence in American adults: a population-based cross-sectional study.美国成年人一天中第一餐时间与胆结石发病率之间的非线性关系：一项基于人群的横断面研究。
Front Nutr. 2024 Dec 16;11:1521707. doi: 10.3389/fnut.2024.1521707. eCollection 2024.
2
An Intermittent Fasting Mimicking Nutrition Bar Extends Physiologic Ketosis in Time Restricted Eating: A Randomized, Controlled, Parallel-Arm Study.一种模拟间歇性禁食的营养棒在限时进食中延长生理性酮症：一项随机、对照、平行臂研究。
Nutrients. 2021 Apr 30;13(5):1523. doi: 10.3390/nu13051523.
3
A Rational Design of a Biphasic DissolutionSetup-Modelling of Biorelevant Kinetics for a Ritonavir Hot-Melt Extruded Amorphous Solid Dispersion.一种双相溶出装置的合理设计——利托那韦热熔挤出无定形固体分散体的生物相关动力学建模
Pharmaceutics. 2020 Mar 6;12(3):237. doi: 10.3390/pharmaceutics12030237.
4
Metformin and AMP Kinase Activation Increase Expression of the Sterol Transporters ABCG5/8 (ATP-Binding Cassette Transporter G5/G8) With Potential Antiatherogenic Consequences.二甲双胍和 AMP 激酶激活增加了固醇转运体 ABCG5/8（三磷酸腺苷结合盒转运蛋白 G5/G8）的表达，具有潜在的抗动脉粥样硬化作用。
Arterioscler Thromb Vasc Biol. 2018 Jul;38(7):1493-1503. doi: 10.1161/ATVBAHA.118.311212. Epub 2018 May 31.
5
Human gallbladder mucosal function: effects on intraluminal fluid and lipid composition in health and disease.人类胆囊黏膜功能：对健康和疾病状态下管腔内液体及脂质成分的影响。
Dig Dis Sci. 1998 Feb;43(2):335-43. doi: 10.1023/a:1018858406560.
6
Meal frequency and duration of overnight fast: a role in gall-stone formation?进餐频率与夜间禁食时长：在胆结石形成中起作用吗？
Br Med J (Clin Res Ed). 1981 Nov 28;283(6304):1435. doi: 10.1136/bmj.283.6304.1435.
7
Effect of fasting and parenteral alimentation on PIPIDA scintigraphy.
Dig Dis Sci. 1983 Aug;28(8):687-91. doi: 10.1007/BF01312557.
8
Gall bladder sludge formation during prolonged fasting after gastrointestinal tract surgery.胃肠道手术后长期禁食期间胆囊泥沙样沉积物的形成
Gut. 1985 Jul;26(7):734-8. doi: 10.1136/gut.26.7.734.
9
Intestinal transit, deoxycholic acid and the cholesterol saturation of bile--three inter-related factors.肠道转运、脱氧胆酸与胆汁胆固醇饱和度——三个相互关联的因素。
Gut. 1986 May;27(5):550-8. doi: 10.1136/gut.27.5.550.
10
Effects of a new, concentrated wheat fibre preparation on intestinal transit, deoxycholic acid metabolism and the composition of bile.一种新型浓缩小麦纤维制剂对肠道转运、脱氧胆酸代谢及胆汁成分的影响。
Gut. 1986 Aug;27(8):893-900. doi: 10.1136/gut.27.8.893.

本文引用的文献

1
The colorimetric determination of phosphorus.磷的比色测定法。
Biochem J. 1932;26(2):292-7. doi: 10.1042/bj0260292.
2
ENZYMATIC DETERMINATION AND THIN-LAYER CHROMATOGRAPHY OF BILE ACIDS IN BLOOD.血液中胆汁酸的酶法测定及薄层色谱分析
J Biochem. 1964 Nov;56:424-31. doi: 10.1093/oxfordjournals.jbchem.a128013.
3
Estimation of cholesterol in bile: assessment of an enzymatic method.胆汁中胆固醇的测定：一种酶法的评估
Clin Chim Acta. 1980 Aug 4;105(2):225-30. doi: 10.1016/0009-8981(80)90464-7.
4
The physicochemical basis of cholesterol gallstone formation in man.人类胆固醇胆结石形成的物理化学基础。
J Clin Invest. 1968 May;47(5):1043-52. doi: 10.1172/JCI105794.
5
The solubility of cholesterol in aqueous solutions of bile salts and lecithin.胆固醇在胆盐和卵磷脂水溶液中的溶解度。
Z Ernahrungswiss. 1971 Apr;10(3):223-33. doi: 10.1007/BF02020933.
6
Bile-rich duodenal fluid as an indicator of biliary lipid composition and its applicability to detection of lithogenic bile.富含胆汁的十二指肠液作为胆汁脂质成分的指标及其在检测致石性胆汁中的适用性。
Am J Dig Dis. 1971 Sep;16(9):797-802. doi: 10.1007/BF02239307.
7
Factors affecting the diurnal variation in the level of -hydroxy- -methylglutaryl coenzyme A reductase and cholesterol-synthesizing activity in rat liver.影响大鼠肝脏中β-羟基-β-甲基戊二酰辅酶A还原酶水平及胆固醇合成活性昼夜变化的因素。
Arch Biochem Biophys. 1972 Sep;152(1):21-7. doi: 10.1016/0003-9861(72)90188-9.
8
In vivo demonstration of the circadian thythm of cholesterol biosynthesis in the liver and intestine of the rat.大鼠肝脏和肠道中胆固醇生物合成昼夜节律的体内实验证明
J Lipid Res. 1972 May;13(3):396-401.
9
Biliary lipid secretion and bile composition after acute and chronic interruption of the enterohepatic circulation in the Rhesus monkey. IV. Primate biliary physiology.恒河猴肝肠循环急性和慢性中断后的胆汁脂质分泌及胆汁成分。IV. 灵长类动物胆汁生理学。
J Clin Invest. 1971 Sep;50(9):1917-26. doi: 10.1172/JCI106684.
10
Letter: A simple calculation of the lithogenic index of bile: expressing biliary lipid composition on rectangular coordinates.信函：胆汁成石指数的简单计算：在直角坐标上表示胆汁脂质成分
Gastroenterology. 1973 Oct;65(4):698-700.

禁食对胆囊胆汁成分的影响。

Effects of fasting on the composition of gallbladder bile.

作者信息

Bloch H M, Thornton J R, Heaton K W

出版信息

Gut. 1980 Dec;21(12):1087-9. doi: 10.1136/gut.21.12.1087.

DOI:10.1136/gut.21.12.1087
PMID:7461468
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1419405/
Abstract

Gallbladder bile was aspirated from the duodenum in nine healthy women after three separate periods of fasting after a standardised meal. Mean cholesterol saturation index was significantly greater after a 15 hour fast (1.35 +/- 0.08) than after a 10 hour fast (1.05 +/- 0.10). However, after 20 hours of fasting, mean cholesterol saturation index had fallen to 1.13 +/- 0.10. Total biliary lipid concentration was unaffected. These findings suggest that fasting has a series of effects on gallbladder bile and that bile sampling should be carried out at at standardised period of time after the last meal.

摘要

在9名健康女性摄入标准餐食后，经过三个不同时长的空腹阶段，从十二指肠抽取胆囊胆汁。平均胆固醇饱和指数在禁食15小时后（1.35±0.08）显著高于禁食10小时后（1.05±0.10）。然而，禁食20小时后，平均胆固醇饱和指数降至1.13±0.10。总胆汁脂质浓度未受影响。这些发现表明，禁食对胆囊胆汁有一系列影响，并且胆汁采样应在最后一餐之后的标准时间段内进行。