Blazer S, Alon U, Berant M, Korman S H
Isr J Med Sci. 1981 Jan;17(1):41-4.
Different rates of renal involvement in the Henoch-Schönlein syndrome have been reported in the literature. We assessed renal involvement during the initial attack of this disease in 71 children in northern Israel, and reevaluated 69 of them after an interval of one to eight years. The mean age at onset was higher than in other reports, and there was a clustering of cases in the late summer and early autumn. During the acute phase of the illness, involvement of the kidney was apparent in only seven patients (9.8%), and only one of these (1.4% of those followed up) showed evidence of continuing renal damage. Patients without initial renal involvement did not subsequently develop renal disease. The remarkably low rate of acute and continuing renal damage in our study as compared with other reports may stem from local variations in causative factors. In our experience, long-term follow-up beyond one year seems warranted only in those patients who had renal involvement during the initial attack.
文献中报道了过敏性紫癜性肾炎的不同发病率。我们评估了以色列北部71名儿童在该疾病初次发作时的肾脏受累情况，并在1至8年的间隔后对其中69名儿童进行了重新评估。发病时的平均年龄高于其他报告，且病例在夏末和初秋有聚集现象。在疾病急性期，只有7名患者（9.8%）出现肾脏受累，其中只有1名患者（随访患者的1.4%）有持续肾脏损害的证据。最初无肾脏受累的患者随后未发生肾脏疾病。与其他报告相比，我们研究中急性和持续肾脏损害的发生率极低，这可能源于致病因素的局部差异。根据我们的经验，似乎只有那些在初次发作时有肾脏受累的患者才需要进行超过一年的长期随访。
