Leroux-Roels G G, Wieme R J, de Broe M E
J Lab Clin Med. 1981 Mar;97(3):316-21.
The presence of circulating enzyme-immunoglobulin complexes was investigated in serum samples of patients with inflammatory bowel disease. In a series of 20 patients with ulcerative colitis AP-Ig complexes were demonstrated in three and LDH-Ig complexes were observed in two others. No AP-Ig or LDH-Ig complexes were found in the sera of 25 patients with Crohn's disease. These findings suggest a relationship between enzyme-immunoglobulin complex formation and ulcerative colitis.
对炎症性肠病患者的血清样本中循环酶 - 免疫球蛋白复合物的存在情况进行了研究。在一系列20例溃疡性结肠炎患者中,有3例检测到碱性磷酸酶 - 免疫球蛋白(AP-Ig)复合物,另有2例观察到乳酸脱氢酶 - 免疫球蛋白(LDH-Ig)复合物。在25例克罗恩病患者的血清中未发现AP-Ig或LDH-Ig复合物。这些发现提示酶 - 免疫球蛋白复合物的形成与溃疡性结肠炎之间存在关联。