Hietanen E
J Toxicol Environ Health. 1980 Sep-Nov;6(5-6):963-9. doi: 10.1080/15287398009529917.
Although many factors influence cancer formation, modification of one factor, diet, may be enough to stop or retard the chain of events leading to the progress of cancer. The role of dietary protein is twofold: proteins supply the body with essential amino acids, but a high-protein diet may enhance the toxicity and even cancer risk of certain environmental xenobiotics to which humans are exposed. Dietary lipids have been correlated epidemiologically with the incidence of breast and colon cancers, although the experimental evidence is scanty. Naturally, the diet should contain as low concentrations of environmental xenobiotics as possible. Food additives such as antioxidants may even be advantageous in the diet, protecting against carcinogenesis by foreign compounds. Further studies are needed before final conclusions can be reached on "noncarcinogenic" diets.
尽管有许多因素会影响癌症的形成,但改变其中一个因素,即饮食,可能足以阻止或延缓导致癌症进展的一系列事件。膳食蛋白质的作用是双重的:蛋白质为身体提供必需氨基酸,但高蛋白饮食可能会增强某些人类接触到的环境异生素的毒性,甚至增加癌症风险。从流行病学角度来看,膳食脂质与乳腺癌和结肠癌的发病率相关,尽管实验证据不足。自然地,饮食中应尽可能含有低浓度的环境异生素。抗氧化剂等食品添加剂甚至可能在饮食中具有益处,可防止外来化合物致癌。在得出关于“非致癌”饮食的最终结论之前,还需要进一步研究。