Quesada Allue L A
Mol Cell Biochem. 1980 Dec 16;33(3):149-55. doi: 10.1007/BF00225287.
Microsome enriched Ceratitis capitata extracts synthesized a glucosylated lipid linked oligosaccharide. Its properties were closely related to those of the previously described insect mannosylated dolichyl diphosphate oligosaccharides and almost the same as those of the rat liver dolichyl-diphosphate-(GlcNAc)2-(Man)9-(Glc)1-3. The saccharide moiety of the latter was transferred to an unknown endogenous protein-like acceptor by the fly extracts. These represent the first evidence of a protein glycosylation in a pluricellular invertebrate through dolichyl derivatives.
富含微粒体的地中海实蝇提取物合成了一种糖基化脂质连接寡糖。其性质与先前描述的昆虫甘露糖基化二磷酸多萜醇寡糖密切相关，几乎与大鼠肝脏二磷酸多萜醇-(N-乙酰葡糖胺)2-(甘露糖)9-(葡萄糖)1-3相同。后者的糖部分被果蝇提取物转移到一种未知的内源性蛋白质样受体上。这些是多细胞无脊椎动物通过多萜醇衍生物进行蛋白质糖基化的首个证据。
