Pertuiset B, Lienhart A, Rosa A, Goutorbe J, Ahmed A
Nouv Presse Med. 1981 Jan 10;10(1):37-9.
The 250 patients of this series, whatsoever was the location of the aneurysm, were operated radically on the 6th and 7th day following the rupture. That is to say at the end of the brain swelling period and before the rebleeding period. During these 5 or 6 days the blood pressure was stabilized by a daily intake of diazepam (15 to 30 millig); 10% only of the patients were resistant; in these cases clonidine was used. During this period antifibrinolitic agents were not given as well as antioedematous therapy. No case of rebleeding was observed in this series under this therapy.
本系列的250例患者，无论动脉瘤位于何处，均在破裂后的第6天和第7天进行了根治性手术。也就是说，在脑肿胀期结束时和再出血期之前。在这5或6天内，通过每日服用地西泮（15至30毫克）来稳定血压；只有10%的患者耐药；在这些情况下使用可乐定。在此期间，未给予抗纤维蛋白溶解剂和抗水肿治疗。在该治疗下，本系列未观察到再出血病例。
