Connor W E
Postgrad Med J. 1980 Aug;56(658):571-4. doi: 10.1136/pgmj.56.658.571.
Epidemiological, laboratory and experimental studies make it clear that dietary cholesterol (DC) and saturated fat, independently and together, are hypercholesterolaemic and atherogenic. Some work suggests that DC, usually given as egg yolk, is the more important, but often they are consumed together. There is a threshold, usually between 100 and 200 mg/day, below which small increments do not affect plasma cholesterol (PC) and another, usually between 500 and 600 mg/day, above which there is little additional change. However, there is considerable individual variation. Recent work suggests that regression of atherosclerosis can occur in the human as in the non-human primate. An alternative, phased, preventive diet has been designed which is nutritionally adequate, ecologically sound, and economical. It also has an historical basis.
流行病学、实验室和实验研究表明，膳食胆固醇（DC）和饱和脂肪单独或共同作用时，都会导致高胆固醇血症并引发动脉粥样硬化。一些研究表明，通常以蛋黄形式摄入的DC更为重要，但它们常常同时被食用。存在一个阈值，通常在每天100至200毫克之间，低于此阈值，少量增加不会影响血浆胆固醇（PC）；另一个阈值通常在每天500至600毫克之间，高于此阈值，变化不大。然而，个体差异相当大。最近的研究表明，人类和非人类灵长类动物一样，动脉粥样硬化可以发生逆转。一种分阶段的预防性饮食方案已经设计出来，它营养充足、生态合理且经济实惠。它也有历史依据。
