Awadhiya R P, Vegad J L, Kolte G N
Res Vet Sci. 1980 Sep;29(2):172-80.
An acute inflammatory response was produced in the chicken by the intraperitoneal injection of turpentine and vascular permeability was assessed by the technique of carbon labelling. This revealed a biphasic pattern of increased permeability which comprised an immediate transient reaction and a delayed more prolonged response. In both phases, the increased permeability remained confined to venules only. The vascular permeability was dissociated in time from leucocyte emigration. The pattern of leucocyte emigration revealed that heterophils and monocytes emigrated concurrently. Participation of basophils in significant numbers in the early stages indicated their possible role in avian inflammation. Examination of mast cells revealed morphological changes of degranulation and disruption. There was a coincident reduction in the population of these cells. It was thought likely that vasoactive amines released from the degranulated mast cells and the basophils might initiate the early vascular changes by acting on the venules.
通过腹腔注射松节油在鸡体内引发急性炎症反应，并采用碳标记技术评估血管通透性。这显示出通透性增加的双相模式，包括即时短暂反应和延迟的更持久反应。在两个阶段中，通透性增加仅局限于小静脉。血管通透性在时间上与白细胞渗出分离。白细胞渗出模式显示嗜异性粒细胞和单核细胞同时渗出。早期大量嗜碱性粒细胞的参与表明它们在禽类炎症中可能发挥的作用。肥大细胞检查显示有脱颗粒和破坏的形态学变化。这些细胞的数量同时减少。据认为，从脱颗粒的肥大细胞和嗜碱性粒细胞释放的血管活性胺可能通过作用于小静脉引发早期血管变化。
