Sinha B K, Vegad J L, Awadhiya R P
Res Vet Sci. 1987 May;42(3):365-72.
Sequential study of permeability and cellular responses following intradermal concanavalin A in the chicken skin, using the colloidal carbon technique, revealed an increase in vascular permeability which was mostly confined to venules. A noteworthy feature of the reaction was marked accumulation of basophils, even in the later stages, and the early appearance of perivascular lymphoid aggregations. The occurrence of well formed giant cells, hypertrophy and hyperplasia of vascular endothelium and marked acanthosis of the epidermis were the other prominent changes. The findings suggest that Con A, in the chicken, appears to have a more general effect on the different types of cells and that it may act as a mitogen not only for T lymphocytes but also for endothelial and epithelial cells.
采用胶体碳技术对鸡皮肤皮内注射伴刀豆球蛋白A后通透性和细胞反应进行的序贯研究显示，血管通透性增加，主要局限于小静脉。该反应的一个显著特征是嗜碱性粒细胞明显聚集，即使在后期也是如此，以及血管周围淋巴样聚集物的早期出现。形成良好的巨细胞、血管内皮细胞肥大和增生以及表皮明显棘皮症的出现是其他突出变化。这些发现表明，伴刀豆球蛋白A在鸡体内似乎对不同类型的细胞有更广泛的作用，并且它不仅可能作为T淋巴细胞的促有丝分裂原，还可能作用于内皮细胞和上皮细胞。
