Shaak T V, Shugaev A I
Vestn Khir Im I I Grek. 1980 Oct;125(10):136-40.
The article is concerned with the role of proteolytic enzymes of the pancreas in the development of renal insufficiency in acute pancreatitis. In 70 patients the activity of tripsin, tripsin inhibitor in the blood were assessed as well as the function of kidneys and morphological alterations in them. The authors propose a scheme of etiopathogenesis of renal insufficiency in acute pancreatitis, the greatest significance being attached to disorders in the systematic and renal hemodyanmics, immunizing inflammation of the connective tissue of the kidneys by the products of pancreas autolysis.
本文关注胰腺蛋白水解酶在急性胰腺炎肾功能不全发展过程中的作用。对70例患者的血液中胰蛋白酶、胰蛋白酶抑制剂活性以及肾脏功能和形态学改变进行了评估。作者提出了急性胰腺炎肾功能不全的病因发病机制方案,其中系统和肾脏血流动力学紊乱以及胰腺自溶产物引起的肾脏结缔组织免疫性炎症具有最重要的意义。