4-氨基吡啶的脑电图研究（作者译）
[Electroencephalographic Investigations of 4-Aminopyridine (author's transl)].
作者信息
Czech K, Gogolák G, Stumpf C
出版信息
Wien Klin Wochenschr. 1980;92(20):734-6.
PMID:7467348
Abstract
Electroencephalographic investigations of 4-aminopyridine were carried out in the non-anesthetized, immobilized rat. Under the influence of this agent seizure-like activity appeared in the hippocampal and subsequently in the neocortical recordings. This effect was antagonized by pretreatment with diazepam. The discussion deals with the central cholinergic action of 4-aminopyridine.
摘要
在未麻醉、固定的大鼠身上进行了4-氨基吡啶的脑电图研究。在这种药物的影响下，海马体记录中出现了癫痫样活动，随后新皮质记录中也出现了这种活动。地西泮预处理可拮抗这种作用。讨论涉及4-氨基吡啶的中枢胆碱能作用。
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