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肾肿瘤评估中的临床与免疫学标准(作者译)

[Clinical and immunological criteria in the evaluation of kidney tumours (author's transl)].

作者信息

Flamm J

出版信息

Wien Med Wochenschr. 1980 Aug 31;130(15-16):523-8.

PMID:7467367
Abstract

A comprehensive clinical and immunological examination was carried out in 32 patients with a condition diagnosed as kidney tumour. The immune status was investigated by in vivo determination of the delayed-type immune reaction by means of cutaneous reactions to primary and recall antigens. The possibilities of differential diagnosis and the value of the individual examinations are discussed from the clinical point of view. Particular importance is attached to angiography and it is pointed out that the first step should always be standard radiography of the aorta suspected because of the pathological vascular structure. On account of the possibility of radiological and clinical masking of renal tumours surgical exposure is recommend if there is the slightest uncertainty. Immunological parameters are not reliable in early and differential diagnosis, since a significant reduction of immunizability does occur in the case of tumours. This phenomenon becomes significant only in patients advanced tumour growth and progressive formation of metastasis.

摘要

对32例被诊断为肾肿瘤的患者进行了全面的临床和免疫学检查。通过对初次和回忆抗原的皮肤反应,以体内测定迟发型免疫反应的方式研究免疫状态。从临床角度讨论了鉴别诊断的可能性和各项检查的价值。血管造影术尤为重要,并指出由于病理性血管结构而怀疑主动脉有问题时,第一步应始终是进行标准的放射照相。鉴于肾肿瘤可能在放射学和临床上被掩盖,所以如果有丝毫不确定性,建议进行手术暴露。免疫参数在早期和鉴别诊断中不可靠,因为肿瘤患者确实会出现免疫能力的显著降低。这种现象仅在肿瘤生长晚期和转移灶逐渐形成的患者中才变得明显。

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