Tin L N, Dauchy F, Girard P, Prestat J, Meunier A, Salamagne J C
Anesth Analg (Paris). 1980;37(11-12):709-12.
Various serum enzyme activities were studied in 15 adult patients before aortography and at the 6th hour and on the first five days after investigation; and at comparable intervals in 8 adult patients who had a bilateral transfemoral arteriography. A significant rise in serum creatine phosphokinase (CPK) level was noted at the 6th hour (p < 0.01), on the 1st day (p < 0.001) and on the 2nd day (p < 0.05) after aortography. Serum aspartate-aminotransferase (ASAT) level increased significantly (p < 0.02) on the 1st day after aortography. No significant change occurred for those two enzymes after transfemoral arteriography. In both groups minor changes were noted for the other enzymes studied: lactic dehydrogenase (LDH), alanineaminotransferase (ALAT) and gamma glutamyl transpeptidase (gamma GT). Rise in CPK and ASAT levels after translumbar aortography is attributable to skeletal muscle trauma and to the retroperitoneal haematoma at the site of puncture. Agents used in anesthesia are apparently not responsible.
对15例成年患者在主动脉造影术前、检查后第6小时以及头五天进行了各种血清酶活性研究；并对8例接受双侧股动脉造影的成年患者在可比间隔时间进行了研究。主动脉造影术后第6小时（p < 0.01）、第1天（p < 0.001）和第2天（p < 0.05）血清肌酸磷酸激酶（CPK）水平显著升高。主动脉造影术后第1天血清天冬氨酸氨基转移酶（ASAT）水平显著升高（p < 0.02）。股动脉造影术后这两种酶无显著变化。在两组中，所研究的其他酶：乳酸脱氢酶（LDH）、丙氨酸氨基转移酶（ALAT）和γ-谷氨酰转肽酶（γ-GT）有轻微变化。经腰主动脉造影术后CPK和ASAT水平升高归因于骨骼肌创伤和穿刺部位的腹膜后血肿。麻醉所用药物显然无责任。
