Barsan W G, Levy R C
Ann Emerg Med. 1981 Mar;10(3):135-7. doi: 10.1016/s0196-0644(81)80377-0.
Many different designs for studies of various aspects of cardiopulmonary resuscitation (CPR) in dogs are described in the literature. No single technique is generally accepted. We present a systematized approach to the study of CPR in the canine model. Cardiac output, arterial blood pressure, and electrocardiogram were recorded for three different methods. The methods studied were closed chest compression, closed chest compression with an automatic gas-powered chest compressor, and open chest manual cardiac massage. Cardiac output for both types of external chest compression were less than 17% of control in all cases. With open chest cardiac massage, systemic arterial blood pressures were in the 50 mm Hg to 100 mm Hg range and cardiac output of up to 70% of control was achieved. Using a metronome to obtain compression rate and the arterial blood pressure to guide the efficacy of compression, consistent levels of cardiac output could be achieved for up to 30 minutes using open chest cardiac massage. Closed chest massage in man results in a cardiac output of 25% to 30% of normal when performed under optimal conditions. A cardiac output of 25% to 30% of control cannot be achieved in large dogs with external chest compression, and hence is not a good model to stimulate CPR in man.
文献中描述了许多用于研究犬心肺复苏（CPR）各个方面的不同设计。没有一种单一技术被普遍接受。我们提出了一种在犬模型中研究心肺复苏的系统化方法。记录了三种不同方法的心输出量、动脉血压和心电图。所研究的方法为闭胸按压、使用自动气体驱动胸部按压器的闭胸按压以及开胸手动心脏按摩。在所有情况下，两种类型的外部胸部按压的心输出量均低于对照的17%。采用开胸心脏按摩时，全身动脉血压在50毫米汞柱至100毫米汞柱范围内，心输出量可达对照的70%。使用节拍器来获得按压频率并以动脉血压指导按压效果，采用开胸心脏按摩可持续30分钟实现一致的心输出量水平。在人类中，在最佳条件下进行闭胸按摩时心输出量为正常的25%至30%。在大型犬中，通过外部胸部按压无法实现对照的25%至30%的心输出量，因此不是模拟人类心肺复苏的良好模型。
