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一项关于有分流和无分流颈动脉内膜切除术的前瞻性研究。

A prospective study of carotid endarterectomy with and without shunt.

作者信息

Ahmad W, Hoffman T H, Fry D E, Harbrecht P J

出版信息

Am Surg. 1981 Jan;47(1):14-8.

PMID:7469170
Abstract

The extent of cerebral protection necessary during carotid endarterectomy for ischemia is controversial. In 147 carotid endarterectomies, carotid backflow was estimated and, in later years, these clinical impressions were correlated with stump pressure. These estimates or values, modified particularly in early years by the extent of contralateral disease and (inversely) of ipsilateral occlusion, were used to determine the need for a shunt at the time of carotid clamping. Only 32 shunts were used, 12 because of poor back bleeding and 20 because of stump pressure below 50 mmHg. The patients who received shunts had no mortality or neurologic deficits. In 30 patients excluded by adequate stump pressure there was only a single minor and temporary monoparesis. In 85 patients excluded by apparently good back bleeding, there were two deaths (one due to stroke), a permanent 10 per cent neurologic deficit, and two postoperative thromboses salvageable by reoperation. Routine shunting would probably have prevented only the temporary monoparesis and the 10 per cent neurologic deficit. Meticulous technique and selective use of a shunt should give satisfactory results.

摘要

颈动脉内膜切除术中缺血时所需的脑保护程度存在争议。在147例颈动脉内膜切除术中,对颈动脉反流进行了评估,在随后的几年里,这些临床观察结果与残端压力进行了关联。这些评估或数值,在早期尤其因对侧疾病的程度以及(呈反比)同侧闭塞的程度而有所修正,被用于确定颈动脉夹闭时是否需要分流。仅使用了32次分流,12次是因为回血不良,20次是因为残端压力低于50 mmHg。接受分流的患者没有死亡或神经功能缺损。在因残端压力足够而被排除的30例患者中,仅有1例轻微且短暂的单瘫。在因回血明显良好而被排除的85例患者中,有2例死亡(1例死于中风),1例永久性10%的神经功能缺损,以及2例术后血栓形成,可通过再次手术挽救。常规分流可能仅能预防短暂的单瘫和10%的神经功能缺损。精细的技术和分流的选择性使用应能带来满意的结果。

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