Coates A L, Boyce P, Shaw D G, Godfrey S, Mearns M
Arch Dis Child. 1981 Feb;56(2):106-11. doi: 10.1136/adc.56.2.106.
This study evaluated the accuracy of the interpretation of the chest film in delineating localised abnormalities of ventilation and perfusion, as well as the overall severity of airways obstruction, exercise tolerance, and clinical condition in children with cystic fibrosis. Radiographic findings in various regions of the chest film were compared with the functional values obtained with regional lung function tests which evaluated the arrival and disappearance of boluses of radioactive nitrogen given by inhalation and infusion. While the more severely affected areas on the chest radiograph were found to correlate with similar regions on the lung function tests, as did overall scores, errors occurred in some cases if the x-ray film alone was used as a judge of regional physiological derangement. In addition the degree of airways obstruction, the exercise tolerance on a cycle ergometer, and clinical grading, each correlated significantly with the radiographic score. We conclude that the chest radiograph is a good indicator of the overall severity of the lung disease and that it correlates well with exercise tolerance and clinical condition in cystic fibrosis.
本研究评估了胸部X光片在描绘囊性纤维化患儿局部通气和灌注异常以及气道阻塞的总体严重程度、运动耐量和临床状况方面的解读准确性。将胸部X光片不同区域的影像学表现与通过区域肺功能测试获得的功能值进行比较，该测试评估吸入和注入放射性氮团注的到达和消失情况。虽然胸部X光片上受影响更严重的区域与肺功能测试中的相似区域相关，总体评分也是如此，但如果仅使用X光片作为区域生理紊乱的判断依据，在某些情况下会出现错误。此外，气道阻塞程度、在自行车测力计上的运动耐量和临床分级，均与影像学评分显著相关。我们得出结论，胸部X光片是肺部疾病总体严重程度的良好指标，并且与囊性纤维化患儿的运动耐量和临床状况密切相关。
