Lévy G, Bachelot C, Joannard A, Bost M
Arch Fr Pediatr. 1980 May;37(5):299-303.
Eight children aged between 4 and 16 years with thalassemia major were treated for 30 months with repeated transfusions and a chelating agent. Deferoxamine was given intravenously for 12 months and subcutaneously in the next 18 months. The results of urine iron concentrations, the practical difficulties of both routes of administration and the clinical results are presented. The therapeutic regime proposed is capable or reducing the iron overload.
8名年龄在4至16岁之间的重型地中海贫血患儿接受了30个月的反复输血及一种螯合剂治疗。去铁胺静脉给药12个月,接下来18个月皮下给药。文中给出了尿铁浓度结果、两种给药途径的实际困难及临床结果。所提出的治疗方案能够减轻铁过载。