Olsson A G, Blombäck M, Ekelund L G
Artery. 1980;7(3):215-23.
In order to study whether the high frequency of exercise ST segment depressions found in primary asymptomatic hyperlipidemia were due to increased plasma fibrinogen levels and blood hematocrit and consequently higher blood viscosity these parameters were determined in fifty-four consecutive hyperlipidemic subjects. Mean plasma fibrinogen as determined by polymerization time was increased in hyperlipidemia. It did not differ between groups with and without exercise ST segment depressions. Mean hematocrit was normal in both men and women. Men with exercise ST segment depressions had lower mean hematocrit than those without (p less than 0.01). The findings speak against the view that the exercise ST segment depressions found in asymptomatic subjects with hyperlipoproteinemia should be due to increased blood viscosity. The most probable cause is a premature, subclinical atherosclerosis.
为了研究在原发性无症状高脂血症中发现的运动性ST段压低的高发生率是否归因于血浆纤维蛋白原水平和血细胞比容的升高以及随之而来的更高的血液粘度，我们对54名连续的高脂血症患者测定了这些参数。通过聚合时间测定的平均血浆纤维蛋白原在高脂血症中升高。有和没有运动性ST段压低的组之间没有差异。男性和女性的平均血细胞比容均正常。有运动性ST段压低的男性的平均血细胞比容低于没有运动性ST段压低的男性（p<0.01）。这些发现与以下观点相悖，即高脂血症无症状患者中发现的运动性ST段压低应归因于血液粘度增加。最可能的原因是过早的亚临床动脉粥样硬化。
