Likholetov S M, Prokof'eva E I, Rogozhkina N M
Zh Mikrobiol Epidemiol Immunobiol. 1978 Sep(9):60-4.
Experiments conducted on non-linear mice demonstrated a possibility of transfer by the intact recipient of delayed hypersensitivity by means of Lawrence'transfer-factor from mice immunized with Coccidioides immitis. The transfer factor administered 48 hours before the intranasal infection protected mice from the lethal dose of coccidioides. This indicated that in coccidioidosis it was possible to transfer delayed hypersensitivity and cellular immunity with the transfer factor.
对非线性小鼠进行的实验表明,用粗球孢子菌免疫的小鼠所产生的迟发型超敏反应,有可能通过Lawrence转移因子由未受感染的受体完整地传递。在鼻内感染前48小时给予的转移因子可保护小鼠免受致死剂量的球孢子菌感染。这表明在球孢子菌病中,有可能通过转移因子传递迟发型超敏反应和细胞免疫。