O'Connor M C, Arias E, Royston J P, Dalrymple I J
Br J Obstet Gynaecol. 1981 Mar;88(3):222-30. doi: 10.1111/j.1471-0528.1981.tb00972.x.
A combined series of 101 twin pregnancies for whom routine hospital rest during the last trimester was replaced by intensified antenatal care in a special twins clinic was studied. Perinatal mortality and morbidity was similar to that found in a comparison group of 137 twin pregnancies under the care of consultants and not referred to the twins clinic. Routine cervical assessments and uterine activity measurements were unhelpful in predicting premature delivery. Urinary oestrogens and ultrasonic measurements of fetal biparietal diameter were of little or no value in predicting weight for gestational age but the ultrasonic measurement of abdominal circumference provided limited information on fetal growth. The contribution of a placebo effect to the results of patients receiving more personalised care cannot be discounted.
对101例双胎妊娠病例进行了综合研究，这些孕妇在妊娠晚期常规的住院休息被在一家特殊的双胎诊所进行的强化产前护理所取代。围产期死亡率和发病率与在顾问医生照料下且未转诊至双胎诊所的137例双胎妊娠对照组中所发现的情况相似。常规的宫颈评估和子宫活动测量对预测早产并无帮助。尿雌激素和胎儿双顶径的超声测量在预测孕周体重方面几乎没有价值，但腹围的超声测量提供了关于胎儿生长的有限信息。安慰剂效应对于接受更个性化护理的患者的结果所起的作用不可忽视。
