Stewart P, Kennedy J H, Barlow D H, Calder A A
Br J Obstet Gynaecol. 1981 Mar;88(3):236-9. doi: 10.1111/j.1471-0528.1981.tb00974.x.
A study was conducted to compare the cervical ripening effect of extra-amniotic prostaglandin E2 with that of extra-amniotic oestradiol valerate in preparation for induction of labour. Sixty primigravidae with an unripe cervix received one or other agent suspended in a viscous gel. The degree of cervical ripening was similar in both groups but more patients treated with prostaglandins became established in labour before planned amniotomy, and poor progress in labour was less common in this group.
为比较羊膜外前列腺素E2与羊膜外戊酸雌二醇在引产准备中的宫颈成熟效果,进行了一项研究。60例宫颈未成熟的初产妇接受了悬浮于粘性凝胶中的一种药物治疗。两组的宫颈成熟程度相似,但使用前列腺素治疗的患者中有更多在计划破膜前进入产程,且该组产程进展不佳的情况较少见。