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[奥地帕林和地夫利尔对大鼠不同器官肾上腺素能神经纤维中儿茶酚胺浓度的影响]

[Effect of odiphalin and difril on catecholamine concentration in adrenergic nerve fibers of different rat organs].

作者信息

Strinskaia L A, Leont'eva G R, Avakian O M, Govyrin V A

出版信息

Biull Eksp Biol Med. 1980 Dec;90(12):698-700.

PMID:7470606
Abstract

The histochemical method of Axelsson coupled with photometry was used to study variations in the content of biogenic amines in different rat organs (myocardium, vas deferens, mesenteric vessels, iris, atrial and ventricular heart valve) under the effect of odiphalin and difril. The results obtained indicate that the organs with direct, indirect and mixed innervation differ in the pattern of response to the pharmacological agents administered. Venous vessels proved to be the most sensitive to the action of odiphalin and difril. The data obtained warrant a conclusion about the heterogeneity of adrenergic nerves in organs and tissues.

摘要

采用阿克塞尔松的组织化学方法并结合光度测定法,研究了在奥地芬林和双嘧哌胺作用下,不同大鼠器官(心肌、输精管、肠系膜血管、虹膜、心房和心室心脏瓣膜)中生物胺含量的变化。所得结果表明,具有直接、间接和混合神经支配的器官对所给药理学药物的反应模式不同。静脉血管被证明对奥地芬林和双嘧哌胺的作用最为敏感。所获得的数据足以得出关于器官和组织中肾上腺素能神经异质性的结论。

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