Peslin R, Hannhart B, Pino J
Bull Eur Physiopathol Respir. 1981 Jan-Feb;17(1):93-105.
Mechanical impedance of the respiratory system was measured at 5, 10, 15 and 20 Hz in 47 healthy non-smokers, 20 ex-smokers and 51 current smokers. Besides the resistance and its frequency dependence, the compliance, the inertance and the resonant frequency of the respiratory system were computed using the assumption of a second order linear system. The data were normalized for sex, age and body height on the basis of correlations observed in non-smokers. No significant difference was found in ex-smokers. In smokers the resistance was significantly increased at all frequencies. However, it was normal in a number of subjects with abnormally low maximal expiratory flows. unlike maximal flows, forced oscillations indices were not correlated to tobacco consumption expressed in pack-years. The results do not indicate that impedance measurements breathing air may be specially useful for early detection of airway abnormalities.
在47名健康非吸烟者、20名曾经吸烟者和51名当前吸烟者中，于5、10、15和20赫兹测量了呼吸系统的机械阻抗。除了阻力及其频率依赖性外，还基于二阶线性系统的假设计算了呼吸系统的顺应性、惯性和共振频率。根据在非吸烟者中观察到的相关性，对数据进行了性别、年龄和身高的标准化处理。曾经吸烟者未发现显著差异。在吸烟者中，所有频率下的阻力均显著增加。然而，在一些最大呼气流量异常低的受试者中，阻力是正常的。与最大流量不同，强迫振荡指标与以包年表示的烟草消费量无关。结果并不表明呼吸空气时的阻抗测量对气道异常的早期检测可能特别有用。
