Christiansen P, Jensen H E, Amdrup E, Fenger C, Lindskov J, Nielsen J, Nielsen S A
Acta Chir Scand. 1978;144(7-8):491-4.
One hundred and eleven (16%) of 701 patients with gastric ulcers, admitted to Kommunehospitalet, Copenhagen, from 1955 to 1964, were 70 years of age of older. Of those elderly patients, 43 were treated surgically, 68 non-surgically. The incidences of hemorrhage and extragastric diseases were significantly greater in older patients, whereas the incidence of pain, site of pain, ulcer size, and location, incidence of combined ulcers and gastric retention did not differ from those observed in younger patients. The duration of symptoms was shorter in the aged, though the difference was not significant. Prognosis was less favourable in the aged, largely due to a higher incidence of hemorrhage (47%) and of accessory diseases (47%). The mortality in elderly patients suffering from hemorrhage and accessory diseases was 64% during hospitalization, but only 4% in patients without accessory diseases. Follow-up and autopsy studies of discharged patients revealed that ulcers healed in only half of the non-surgical patients and that surgery was ultimately necessary in 50% of these. It was concluded that the factors which prescribed surgical treatment in elderly patients with gastric ulcers did not differ considerably from those in younger patients. The risk was greater, but this was also true in non-surgical treatment. Close cooperation between surgeon and physician was essential, both pre- and postoperatively, since accessory diseases were very significant for the outcome.
1955年至1964年期间,哥本哈根市立医院收治的701例胃溃疡患者中,有111例(16%)年龄在70岁及以上。在这些老年患者中,43例接受了手术治疗,68例接受了非手术治疗。老年患者出血和胃外疾病的发生率明显更高,而疼痛发生率、疼痛部位、溃疡大小和位置、复合溃疡发生率以及胃潴留情况与年轻患者观察到的情况并无差异。老年患者症状持续时间较短,尽管差异不显著。老年患者的预后较差,主要原因是出血发生率较高(47%)和并存疾病发生率较高(47%)。患有出血和并存疾病的老年患者住院期间死亡率为64%,但无并存疾病的患者死亡率仅为4%。对出院患者的随访和尸检研究表明,非手术治疗的患者中只有一半溃疡愈合,其中50%最终仍需要手术治疗。得出的结论是,老年胃溃疡患者手术治疗的指征与年轻患者相比没有太大差异。风险更大,但非手术治疗也是如此。外科医生和内科医生在术前和术后密切合作至关重要,因为并存疾病对治疗结果影响很大。